Methylparaben → HCID 12297133, compound

Participants

Reaction Steps

With 100 ml of 2-butanone were mixed 20.0 g (79.6 mmol) of 11-bromoundecane-1-ol, 11.0 g (72.5 mmol) of methyl p-hydroxybenzoate, and 10.0 g (72.4 mmol) of potassium carbonate. The whole was refluxed for 48 hours. Upon cooling the reaction mixture to room temperature, a large amount of precipitate appeared. The precipitate was collected by filtration under washing with hexane and dried to obtain 20.2 g of methyl p-(11-hydroxyundecyloxy)benzoate (1) (yield: 86.7%).

Provenance & Evidence