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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 742635Generated: November 1, 2026

N-methoxyacetyl-2-(3,4-dichlorophenyl)-4-(tetrahydropyran-2-yloxy)butylamin → N-(2-methoxyethyl)-2-(3,4-dichlorophenyl)-4-(tetrahydropyran-2-yloxy)butylamine

https://huagongshe.com/reaction/742635

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-methoxyacetyl-2-(3,4-dichlorophenyl)-4-(tetrahydropyran-2-yloxy)butylaminHCID 19705334—
ReactantAluminium lithium hydrideHCID 21226445—
SolventTetrahydrofuranHCID 8028—
ProductN-(2-methoxyethyl)-2-(3,4-dichlorophenyl)-4-(tetrahydropyran-2-yloxy)butylamineHCID 19705336—

Reaction Steps

A suspension of 1.5 g of LiAlH4 in 30 ml of tetrahydrofuran (THF) is refluxed and a solution of 7.5 g of the product obtained in step 1 in 40 ml of THF are added dropwise thereto.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05554763
Source datasetuspto-grants-1996_09
ORD IDord-c9849f01856d4416bcb1611129eb9d28
Source noteuspto-grants-1996_09