Acetone → HCID 11402885, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 2.126 g (17.4 mmol) of 3,4-dimethylphenol, 98 mg (1.69 mmol) of acetone, and 20.9 mg (0.22 mmol) of methanesulfonic acid was heated for 62 hours at 100° C. and then at 150° C. for 26 hours. The mixture was allowed to cool, diluted with 30 mL of toluene, and washed three times with a 10% aqueous NaOH solution, water and brine. The organic layer was dried over MgSO4 and then concentrated under reduced pressure. There was obtained 335 mg of crude 2,3,6,7,9,9-hexamethylxanthene as a tan solid.

Provenance & Evidence