Methanol → (2S,3S,5S)-2,5-Bis-(N-(N-((N-methyl-N-((2-amino-4-thiazolyl)methyl)amino)carbonyl)valinyl)amino)-1,6-diphenyl-3-hydroxyhexane

Participants

Reaction Steps

Using the procedure of Example 58B but replacing the resultant compound of Example 58A with the resultant compound of Example 94 provided, after silica gel chromatography using first 5% then 10% methanol in chloroform, 52 mg (72%) of the desired compound (Rf 0.18, 10% methanol in chloroform) as a white solid, m.p. 110°-114° C. Mass spectrum: (M+1)+ =821.

Provenance & Evidence