Sodium Hydroxide → HCID 178460564, compound

HRID 742940Notes

Reaction equation

HRID 742940 reaction equation
[PH:1](=[O:16])([O-:15])[O:2][C:3](CC)([CH2:11][CH3:12])[N:4]([CH2:8][CH2:9][OH:10])[CH2:5][CH2:6][OH:7].[OH-].[Na+:18]>O>[PH:1](=[O:15])([O-:16])[O:2][CH:3]([CH2:11][CH3:12])[N:4]([CH2:5][CH2:6][OH:7])[CH2:8][CH2:9][OH:10].[Na+:18]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 178447638HCID 178447638, compound

Product 1

HCID 178460564HCID 178460564, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
80 °C

Procedure

This intermediate was prepared by adding 256 parts of diethyl-N,N-bis(hydroxyethyl)aminomethyl phosphonate to a 14% by weight solution of sodium hydroxide in water in a stirred reactor equipped with a distillation column and heating the mixture slowly to cause distillation of by-product ethanol to begin. The column temperature was maintained at 72°-75° C. and the reactor temperature was maintained at 80° C. until distillation stopped. The pH of the cooled product was 10.1 and the percent solids was 51.7.

Workup

  1. customThis intermediate was prepared
  2. customequipped with a distillation column
  3. temperatureheating the mixture slowly
  4. distillationdistillation of by-product ethanol
  5. temperatureThe column temperature was maintained at 72°-75° C.

Sources & evidence

ORD record
ord-b823067a6e2c43c8999694f419b99aad
Source dataset
uspto-grants-1996_09
Patent number
US05556698

Reaction notes

Loading…