HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl cyanoacetate → HCID 67736244, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl cyanoacetate | HCID 7764 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 108656-33-3 | HCID 46781586 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 67736244 | HCID 67736244 | — |
Reaction Steps
A mixture of (1R,2S )-2-amino-3-fluoro-1-(4-methylsulfonylphenyl)-1-propanol hydrochloride (5.66 g; 20 mmol), absolute ethanol (27 ml), ethyl cyanoacetate (22.62 g; 200 mmol) and triethylamine (3.03 g; 30 mmol) was refluxed for 21 hours.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05556829 |
| Source dataset | uspto-grants-1996_09 |
| ORD ID | ord-d5c9bb60fd8a48b9864b5f6a6c000f77 |
| Source note | uspto-grants-1996_09 |