HCID 19423610, compound → HCID 19423595, compound

Participants

Reaction Steps

To a solution of 2.0 g (4.66 mmol) of 3-[2(diethylamino)ethyl]-4-(3-benzyloxyphenyl)-3,4-dihydro-2(1H)-quinazolinone in 100 mL of methanol was added 200 mg of 5 % palladium-carbon, and the mixture was stirred for 5 hours under a hydrogen atmosphere at ambient temperature. The reaction mixture was filtered through cerite, and the filtrate was concentrated in vacuo. The crystals formed was recrystallized from methanol to give 1.30 g (3.83 mmol) of the title compound.

Provenance & Evidence