HCID 19423564, compound → HCID 19423548, compound

Participants

Reaction Steps

To a solution of 700 mg (1.32 mmol) of 3-[1-(3-benzyloxycarbonylbenzyl)piperidin-4-yl]-4-phenyl-3,4-dihydro-2(1H)-quinazolinone in acetic acid was added 50 mg 10 % palladium-carbon, and the mixture was stirred for 5 hours in a hydrogen atmosphere at ambient temperature. The reaction mixture was filtered through cerite, and the filtrate was concentrated in vacuo. The resulting crude crystals were recrystallized from ethanol to give 450 mg (1.02 mmol) of the title compound.

Provenance & Evidence