Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
methyl 4-(1-methyl-1H-indol-3-yl)butanoate → 4-(2-oxo-2,3-dihydro-1H-indol-3-yl)butanoic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | methyl 4-(1-methyl-1H-indol-3-yl)butanoate | HCID 3345143 | — |
| 반응물 | DMSO HCl | HCID 12206146 | — |
| 생성물 | 4-(2-oxo-2,3-dihydro-1H-indol-3-yl)butanoic acid | HCID 2764088 | — |
| 생성물 | 4-(1-Methyl-2-oxo-3-indolinyl)butanoic acid | HCID 14956204 | — |
반응 단계
Reaction of the ester [II: R1 =R3 =H, R2 =(CH2)3COOMe, R3 =Me] with DMSO/HCl as above gave crude 4-(1-methyl-2-oxo-3-indolinyl)butanoic acid [III: R1 =R3 =H, R2 =(CH2)3COOMe, R3 =Me] (0.84 g, 91% yield) as a brown oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05556874 |
| 출처 데이터셋 | uspto-grants-1996_09 |
| ORD ID | ord-5ad9f63ff24141d4a4ff315395c0e8cd |
| 출처 메모 | uspto-grants-1996_09 |