反应详情

The whole of this 2-benzyloxystilbene was dissolved in 300 ml of ethanol, and the resulting solution was stirred at 60° C. for 3.5 hours in an atmosphere of hydrogen at atmospheric pressure and in the presence of 1.00 g of 5% w/w palladium-on-charcoal. The catalyst was removed by filtration, and the filtrate was concentrated by distillation under reduced pressure. The resulting residue was then purified by column chromatography through silica gel, using a 4:1 by volume mixture of hexane and ethyl acetate as the eluent, to give 6.41 g (yield 89%) of the title compound as a colorless solid.

1. customThe catalyst was removed by filtration
2. concentrationthe filtrate was concentrated by distillation under reduced pressure
3. customThe resulting residue was then purified by column chromatography through silica gel
4. additionby volume mixture of hexane and ethyl acetate as the eluent