Ethanol → HCID 178469373, compound

HRID 743678Notes

Reaction equation

HRID 743678 reaction equation
Cl.[NH2:2][NH2:3].C([C:6](CC)([C:10]([C:12]([O-:14])=[O:13])=O)[C:7]([O-:9])=O)C.[Na+].[Na+].[CH2:19](O)[CH3:20]>>[CH2:19]([O:14][C:12]([C:10]1[CH:6]=[C:7]([OH:9])[NH:3][N:2]=1)=[O:13])[CH3:20]

Participants

4

Reactant 3

HCID 702EthanolHCID 115031Hydrazinium chlorideHCID 23179480Diethyloxalacetate sodium

Product 1

HCID 178469373HCID 178469373, compound

Procedure

To 400 ml of ethanol were added 20.6 g (0.30 mol) of the hydrazine hydrochloride and 63.0 g (0.30 mol) of sodium diethyloxalacetate. This mixture was stirred at room temperature for 2 hours, and then heated with refluxing and stirring for 3 hours. After the ethanol was distilled off, 100 ml of water was added to the residue. The resulting mixture was stirred at room temperature for 1 hour, and the crystals yielded were taken out by filtration and washed with water.

Workup

  1. temperatureheated
  2. temperaturewith refluxing
  3. stirringstirring for 3 hours
  4. distillationAfter the ethanol was distilled off
  5. addition100 ml of water was added to the residue
  6. stirringThe resulting mixture was stirred at room temperature for 1 hour
  7. customthe crystals yielded
  8. filtrationwere taken out by filtration
  9. washwashed with water

Sources & evidence

ORD record
ord-8267474760ef42e49374e151e119e192
Source dataset
uspto-grants-1996_09
Patent number
US05556987

Reaction notes

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