反应详情

To 800 ml of ethanol were added 108 g (1.1 mol) of sulfuric acid, 92.1 g (2.0 mol) of methylhydrazine, and 462.4 g (2.20 mol) of sodium diethyloxalacetate. This mixture was stirred at room temperature for 2 hours, and then heated with refluxing and stirring for 3 hours. After the ethanol was distilled off, 800 ml of water was added to the residue. The resulting mixture was allowed to stand at room temperature overnight, and the crystals yielded were taken out by filtration and washed with water. Yield: 279 g (82%). Melting point: 151°-153° C.

1. temperatureheated
2. temperaturewith refluxing
3. stirringstirring for 3 hours
4. distillationAfter the ethanol was distilled off
5. addition800 ml of water was added to the residue
6. waitto stand at room temperature overnight
7. customthe crystals yielded
8. filtrationwere taken out by filtration
9. washwashed with water