HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → 5-(difluoromethoxy)-1-methyl-1H-pyrazole-3-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | Methyl 5-(difluoromethoxy)-1-methyl-1H-pyrazole-3-carboxylate | HCID 54319416 | — |
| Product | 5-(difluoromethoxy)-1-methyl-1H-pyrazole-3-carboxamide | HCID 53731990 | — |
Reaction Steps
80.6 g (0.39 mole) 3-Methoxycarbonyl-5-difluoromethoxy-1-methylpyrazole and 300 ml aqueous ammonia (33%) was stirred under reflux for 1 hour. The reaction solution was cooled, the precipitate filtered off and washed with water and diisopropyl ether.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05556986 |
| Source dataset | uspto-grants-1996_09 |
| ORD ID | ord-7836b4437f3845bc910f88da2d8c435d |
| Source note | uspto-grants-1996_09 |