Water → 1-Benzyloxy-7-cyano-3-hydrazino-6-trifluoromethylquinoxalin-2(1H)-one

Participants

Reaction Steps

To a solution of 5.2 g (13.7 mmol) of 1-benzyloxy-3-chloro-7-cyano-6-trifluoromethylquinoxalin-2(1H)-one in 150 ml of dichloromethane was added 2.7 ml of hydrazine monohydrate (~55.7 mmol) at 0° C. Stirring was continued at 0° C. for 1 h. The evaporated reaction mixture was stirred with water to give the title compound (5.0 g; 97%).

Provenance & Evidence