Phenethyl isocyanate → HCID 178523199, compound

HRID 744044Notes

Reaction equation

HRID 744044 reaction equation
[C:1]1([CH2:7][CH2:8][N:9]=[C:10]=[O:11])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[NH:12]1[CH:16]=[C:15]([CH2:17][CH2:18][OH:19])[N:14]=[CH:13]1>>[C:1]1([CH2:7][CH2:8][NH:9][C:10](=[O:11])[O:19][CH2:18][CH2:17][C:15]2[N:14]=[CH:13][NH:12][CH:16]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 160602Phenethyl isocyanateHCID 178520346HCID 178520346, compound

Product 1

HCID 178523199HCID 178523199, compound

Procedure

The preparation is carried out as in Example 23 with 2-phenylethyl isocyanate and 2-(1H-imidazol-4-yl)ethanol. The title compound is extracted from water with dichloromethane, purified by chromatography and crystallized in the hydrogenmaleate form from ethanol/diethyl ether.

Workup

  1. extractionThe title compound is extracted from water with dichloromethane
  2. custompurified by chromatography
  3. customcrystallized in the hydrogenmaleate form from ethanol/diethyl ether

Sources & evidence

ORD record
ord-38dbd7d112d44573a27ee34fa66ac480
Source dataset
uspto-grants-1996_09
Patent number
US05559113

Reaction notes

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