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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 74415Generated: October 25, 2026

Acetonitrile → 3-Hydroxy-3-(3-(2-hydroxy-2-phenylethoxy)phenyl)propanenitrile

https://huagongshe.com/reaction/74415

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetonitrileHCID 6342—
Reactant3-(2-Hydroxy-2-phenylethoxy)benzaldehydeHCID 60708533—
Product3-Hydroxy-3-(3-(2-hydroxy-2-phenylethoxy)phenyl)propanenitrileHCID 67317027—

Reaction Steps

Addition of acetonitrile to 3-(2-hydroxy-2-phenylethoxy)benzaldehyde gave 3-hydroxy-3-(3-(2-hydroxy-2-phenylethoxy)phenyl)propanenitrile as a yellow oil. Yield (0.97 g, crude): MS: 284 [M+1]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08829244B2
Source datasetuspto-grants-2014_09
ORD IDord-f73fb67ab6c04a548fd65f2c3e480400
Source noteuspto-grants-2014_09