Mercapto-ethanol → HCID 135484501, compound

Participants

Reaction Steps

A mixture of 12 (0.58 g, 0.88 mmol), mercaptoethanol (0.25 ml, 3.53 mmol) and NaOMe (0.76 ml, 3.53 mmol, 35% weight solution in MeOH (10 ml)) was refluxed for six hours. The reaction mixture was cooled, neutralized with glacial acetic acid and evaporated to dryness. The solid obtained was washed with CHCl3 and the residue was crystallized from water to yield pure 13 (0.215 g, 86%) as white crystal: m.p. 248° C. (dec).

Provenance & Evidence