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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 74435Generated: October 29, 2026

Ethanol → HCID 178432251, compound

https://huagongshe.com/reaction/74435

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthanolHCID 702—
ReactantSodium HydroxideHCID 14798—
ReactantHCID 178432250HCID 178432250—
SolventWaterHCID 962—
ProductHCID 178432251HCID 17843225164.1%

Reaction Steps

An aqueous solution (1.67 ml) of 4 M sodium hydroxide was added to an ethanol solution (17 ml) of [5-amino-1-(2-methyl-1H-benzimidazol-5-yl)-1H-pyrazol-4-yl]-(1-benzenesulfonyl-1H-indol-2-yl)methanone (87 mg). The resulting mixture was stirred at room temperature for 2 hours. The reaction mixture was poured into water. The resulting solid was collected by filtration, washed with water, and dried to give [5-amino-1-(2-methyl-1H-benzimidazol-5-yl)-1H-pyrazol-4-yl]-(1H-indol-2-yl)methanone (40 mg, 63%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08829199B2
Source datasetuspto-grants-2014_09
ORD IDord-0062a590272543ee9a737676ba1c8fd1
Source noteuspto-grants-2014_09