HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → HCID 178432251, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 178432250 | HCID 178432250 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 178432251 | HCID 178432251 | 64.1% |
Reaction Steps
An aqueous solution (1.67 ml) of 4 M sodium hydroxide was added to an ethanol solution (17 ml) of [5-amino-1-(2-methyl-1H-benzimidazol-5-yl)-1H-pyrazol-4-yl]-(1-benzenesulfonyl-1H-indol-2-yl)methanone (87 mg). The resulting mixture was stirred at room temperature for 2 hours. The reaction mixture was poured into water. The resulting solid was collected by filtration, washed with water, and dried to give [5-amino-1-(2-methyl-1H-benzimidazol-5-yl)-1H-pyrazol-4-yl]-(1H-indol-2-yl)methanone (40 mg, 63%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08829199B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-0062a590272543ee9a737676ba1c8fd1 |
| Source note | uspto-grants-2014_09 |