Methyl iodide → 3-(3-Pentyloxy-1,2,5-thiadiazol-4-yl)-1-methylpyridinium iodide

HRID 744602Notes

Reaction equation

HRID 744602 reaction equation
[CH3:1][I:2].[CH2:3]([O:8][C:9]1[C:10]([C:14]2[CH:15]=[N:16][CH:17]=[CH:18][CH:19]=2)=[N:11][S:12][N:13]=1)[CH2:4][CH2:5][CH2:6][CH3:7]>CC(C)=O>[I-:2].[CH2:3]([O:8][C:9]1[C:10]([C:14]2[CH:15]=[N+:16]([CH3:1])[CH:17]=[CH:18][CH:19]=2)=[N:11][S:12][N:13]=1)[CH2:4][CH2:5][CH2:6][CH3:7]

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 151801343-(3-Pentyloxy-1,2,5-thiadiazol-4-yl)pyridine

Product 1

HCID 190755023-(3-Pentyloxy-1,2,5-thiadiazol-4-yl)-1-methylpyridinium iodide

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

A mixture of methyl iodide (0.3 ml, 5 mmol) and 3-(4-pentyloxy-1,2,5-thiadiazol-3-yl)pyridine (620 mg, 2.5 mmol) in acetone (5 ml) was stirred at room temperature for 18 h. The title compound precipitated from the solution and was collected by filtration to yield 0.81 g (84%).

Workup

  1. customThe title compound precipitated from the solution
  2. filtrationwas collected by filtration
  3. customto yield 0.81 g (84%)

Sources & evidence

ORD record
ord-c62922024c384067a5556563fe01cd24
Source dataset
uspto-grants-1996_09
Patent number
US05559138

Reaction notes

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