Methyl iodide → 3-(4-Chloro-1,2,5-thiadiazol-3-yl)-1-methylpyridinium iodide

HRID 744617Notes

Reaction equation

HRID 744617 reaction equation
[Cl:1][C:2]1[C:3]([C:7]2[CH:8]=[N:9][CH:10]=[CH:11][CH:12]=2)=[N:4][S:5][N:6]=1.[CH3:13][I:14]>CC(C)=O>[I-:14].[Cl:1][C:2]1[C:3]([C:7]2[CH:8]=[N+:9]([CH3:13])[CH:10]=[CH:11][CH:12]=2)=[N:4][S:5][N:6]=1

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 104881643-Chloro-4-(pyridin-3-yl)-1,2,5-thiadiazole

Product 1

HCID 190753343-(4-Chloro-1,2,5-thiadiazol-3-yl)-1-methylpyridinium iodideYield 100.1%

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

A solution of 3-(4-chloro-1,2,5-thiadiazol-3-yl)pyridine (1.98 g, 10 mmol) and methyl iodide (4.25 g, 30 mmol) in acetone (10 ml) was stirred at room temperature for 16 h. The precipitate was collected by filtration to yield 3.40 g (100%) of the title compound.

Workup

  1. filtrationThe precipitate was collected by filtration

Sources & evidence

ORD record
ord-cc3a7debfc7c40499a5e1ff44c2bfb29
Source dataset
uspto-grants-1996_09
Patent number
US05559138

Reaction notes

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