Methyl iodide → HCID 19075341, compound

HRID 744671Notes

Reaction equation

HRID 744671 reaction equation
[CH3:1][I:2].[C:3]([NH:6][C:7]1[C:8]([C:12]2[CH:13]=[N:14][CH:15]=[CH:16][CH:17]=2)=[N:9][O:10][N:11]=1)(=[O:5])[CH3:4]>CC(C)=O>[I-:2].[C:3]([NH:6][C:7]1[C:8]([C:12]2[CH:13]=[N+:14]([CH3:1])[CH:15]=[CH:16][CH:17]=2)=[N:9][O:10][N:11]=1)(=[O:5])[CH3:4]

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 19075446HCID 19075446, compound

Product 1

HCID 19075341HCID 19075341, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

Methyl iodide (450 μl, 7.2 mmol) was added to a solution of 3-(4-acetylamino-1,2,5-oxadiazol-3-yl )pyridine (490 mg, 2.4 mmol) in acetone. The reaction mixture was stirred at room temperature for 18 h and the precipitate collected by filtration. Yield: 640 mg (77% ).

Workup

  1. filtrationthe precipitate collected by filtration

Sources & evidence

ORD record
ord-08d1fd8dff644cfa99ac69b09a1cc529
Source dataset
uspto-grants-1996_09
Patent number
US05559138

Reaction notes

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