HCID 19422037, compound → HCID 54201434, compound

HRID 744716Notes

Reaction equation

HRID 744716 reaction equation
[CH2:1]([N:8]1[C:12]([C:13](O)([C:23]2[CH:28]=[CH:27][C:26]([C:29]([NH:31]C(C)(C)C)=O)=[CH:25][CH:24]=2)[CH2:14][CH2:15][CH2:16][C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)=[CH:11][N:10]=[CH:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>S(Cl)(Cl)=O>[CH2:1]([N:8]1[C:12]([C:13]([C:23]2[CH:28]=[CH:27][C:26]([C:29]#[N:31])=[CH:25][CH:24]=2)=[CH:14][CH2:15][CH2:16][C:17]2[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=2)=[CH:11][N:10]=[CH:9]1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 1

HCID 19422037HCID 19422037, compound

Product 1

HCID 54201434HCID 54201434, compound

Reagents, catalysts & solvents 1

HCID 24386Thionyl ChlorideSolvent

Procedure

1,95 g of 1-benzyl-5-[1-hydroxy-4-phenyl-1-(4-tert-butylaminocarbonylphenyl)butyl]-1H-imidazole is refluxed 2 hours in 40 ml of thionyl chloride.

Sources & evidence

ORD record
ord-3a2ccad3f2c148f1acf36edd3aa783c5
Source dataset
uspto-grants-1996_09
Patent number
US05559141

Reaction notes

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