Dimethylamine → HCID 19422656, compound

HRID 744905Notes

Reaction equation

HRID 744905 reaction equation
[C:1]([NH:4][C:5]1[CH:10]=[C:9]2[O:11][CH2:12][O:13][C:8]2=[CH:7][C:6]=1[C:14](=[O:17])[CH2:15]Cl)(=[O:3])[CH3:2].[CH3:18][NH:19][CH3:20]>>[C:1]([NH:4][C:5]1[CH:10]=[C:9]2[O:11][CH2:12][O:13][C:8]2=[CH:7][C:6]=1[C:14](=[O:17])[CH2:15][N:19]([CH3:20])[CH3:18])(=[O:3])[CH3:2]

Participants

3

Reactant 2

HCID 674DimethylamineHCID 10264361HCID 10264361, compound

Product 1

HCID 19422656HCID 19422656, compound

Procedure

2'-Acetylamino-4',5'-methylenedioxy-2-chloroacetophenone, prepared in Example 1, part (B), is reacted with an excess of dimethylamine under similar conditions as taught in Example 1, part (H), to yield 2'-acetylamino-4',5'-methylenedioxy-2-dimethylaminoacetophenone which is turn is deprotected by the procedure of Example 1, part (E), to yield 2'-amino-4',5'-methylenedioxy-2-dimethylaminoacetophenone.

Sources & evidence

ORD record
ord-b3138d38a8894d02ab8598bb15781354
Source dataset
uspto-grants-1996_09
Patent number
US05559235

Reaction notes

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