HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chloroform → Ammonium Hydroxide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chloroform | HCID 6212 | — |
| Reactant | tert-Butyl carbamate | HCID 77922 | — |
| Reactant | HCID 78186916 | HCID 78186916 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Ammonium Hydroxide | HCID 14923 | — |
| Product | HCID 78186916 | HCID 78186916 | — |
Reaction Steps
Alternatively, Compound 175e was prepared as follows. Compound 174 was converted to the title Compound 175e by a procedure analogous to that used for the synthesis of Compound 21. Flash chromatography (100% CHCl3 to CHCl3 --MeOH--NH4OH: 0:4.5:0.5) on a silica gel column gave Compound 175e as a white solid which was lyophilized from 1,4-dioxane to give a white lyophilate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05559256 |
| Source dataset | uspto-grants-1996_09 |
| ORD ID | ord-1c4b9666e6c241a385c0cd96bcb3bcc9 |
| Source note | uspto-grants-1996_09 |