HCID 86749868, compound → HCID 86749867, compound

HRID 745129Notes

Reaction equation

HRID 745129 reaction equation
N#N.[OH:3][CH:4](CO)[CH2:5][O:6][C:7]([NH:9][C@H:10]([C:14]([NH:16][CH:17]([CH2:41][C:42]1[CH:47]=[CH:46][CH:45]=[CH:44][CH:43]=1)[CH:18]([OH:40])[CH2:19][NH:20][CH2:21][CH:22]([OH:39])[CH:23]([NH:31][C:32]([O:34][C:35]([CH3:38])([CH3:37])[CH3:36])=[O:33])[CH2:24][C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1)=[O:15])[CH:11]([CH3:13])[CH3:12])=[O:8]>CO>[CH3:37][C:35]([CH3:36])([O:34][C:32]([NH:31][CH:23]([CH2:24][C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1)[CH:22]([OH:39])[CH2:21][NH:20][CH2:19][CH:18]([OH:40])[CH:17]([NH:16][C:14](=[O:15])[C@H:10]([CH:11]([CH3:13])[CH3:12])[NH:9][C:7]([O:6][CH2:5][CH2:4][OH:3])=[O:8])[CH2:41][C:42]1[CH:47]=[CH:46][CH:45]=[CH:44][CH:43]=1)=[O:33])[CH3:38]

Participants

3

Reactant 1

HCID 86749868HCID 86749868, compound

Product 1

HCID 86749867HCID 86749867, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Compounds 218b and 54 were converted to the title Compound 218c (white solid) by a two-step procedure analogous to that used for the conversion of Compound 202c to Compound 202e. m.p.=174°-179° C.; [α]D =-16.1° (c =0.23; MeOH) High resolution MS (FAB): Calculated (M+H)+ (for C33H51N4O8)=631.3707; Observed (M+H)+ =631.3709 Δ=0.3 ppm

Sources & evidence

ORD record
ord-3f94718ed8e14d94896d7e35d3bbeba7
Source dataset
uspto-grants-1996_09
Patent number
US05559256

Reaction notes

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