N-[2-[(4-chlorophenyl)sulfonyl]ethyl]-N-(1-methylethyl)carbamic acid phenyl ester → N-[2-(4-chlorophenylsulfonyl)ethyl]-2-propanamine hydrochloride

HRID 745168Notes

Reaction equation

HRID 745168 reaction equation
C1(OC(=O)N(CCS(C2C=CC([Cl:24])=CC=2)(=O)=O)C(C)C)C=CC=CC=1.C1(OC(=O)[N:34]([CH2:38][CH2:39][S:40]([C:43]2[CH:48]=[CH:47][C:46]([Cl:49])=[C:45](Cl)[CH:44]=2)(=[O:42])=[O:41])[CH:35]([CH3:37])[CH3:36])C=CC=CC=1>>[ClH:24].[Cl:49][C:46]1[CH:45]=[CH:44][C:43]([S:40]([CH2:39][CH2:38][NH:34][CH:35]([CH3:37])[CH3:36])(=[O:41])=[O:42])=[CH:48][CH:47]=1

Participants

3

Reactant 2

HCID 13655163N-[2-[(4-chlorophenyl)sulfonyl]ethyl]-N-(1-methylethyl)carbamic acid phenyl esterHCID 54250551HCID 54250551, compound

Product 1

HCID 13655033N-[2-(4-chlorophenylsulfonyl)ethyl]-2-propanamine hydrochloride

Procedure

When in the procedure of Preparation 29, N-[2-[(4-chlorophenyl)sulfonyl]ethyl]-N-(1-methylethyl)carbamic acid phenyl ester is substituted for N-[2-[(3,4-dichlorophenyl)sulfonyl]ethyl]-N-(1-methylethyl)carbamic acid phenyl ester, the title compound is obtained.

Sources & evidence

ORD record
ord-acb31b6c86404b5bbb40ad23747db0ac
Source dataset
uspto-grants-1986_07
Patent number
US04597902

Reaction notes

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