Methyl formate → HCID 13120661, compound

HRID 745225Notes

Reaction equation

HRID 745225 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:11]2[NH:16][CH2:15][CH2:14][NH:13][C:12]2=[O:17])[CH:6]=[CH:7][C:8]=1[O:9][CH3:10].[CH:18](OC)=[O:19]>>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:11]2[N:16]([CH:18]=[O:19])[CH2:15][CH2:14][NH:13][C:12]2=[O:17])[CH:6]=[CH:7][C:8]=1[O:9][CH3:10]

Participants

3

Reactant 2

HCID 7865Methyl formateHCID 13120656HCID 13120656, compound

Product 1

HCID 13120661HCID 13120661, compound

Procedure

23.6 g (0.1 mol) of 3-(3,4-dimethoxyphenyl)-piperazin-2-one, prepared in accordance with Example 1, are heated at 110° C. with 150 ml of methyl formate for 3 hours in an autoclave. The residue remaining after the mixture has been concentrated in vacuo is triturated with ether, filtered off with suction and dried.

Workup

  1. concentrationhas been concentrated in vacuo
  2. customis triturated with ether
  3. filtrationfiltered off with suction
  4. customdried

Sources & evidence

ORD record
ord-440b6e6aa774423f96f2746679c7e195
Source dataset
uspto-grants-1986_07
Patent number
US04598079

Reaction notes

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