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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 745228Generated: October 31, 2026

Benzyl Chloride → 3-(4-Fluorophenyl)-4-benzylpiperazin-2-one

https://huagongshe.com/reaction/745228

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzyl ChlorideHCID 7503—
Reactant3-(4-Fluorophenyl)piperazin-2-oneHCID 13120669—
Product3-(4-Fluorophenyl)-4-benzylpiperazin-2-oneHCID 13120670—

Reaction Steps

25 g (0.129 mol) of 3-(4-fluorophenyl)-piperazin-2-one, prepared in accordance with Example 13, are alkylated with 18.1 g (0.143 mol) of benzyl chloride, as described in Example 2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04598079
Source datasetuspto-grants-1986_07
ORD IDord-1158a0385ba44c34a88864c70e084a09
Source noteuspto-grants-1986_07