Methyl chloroacetate → HCID 13120682, compound

HRID 745234Notes

Reaction equation

HRID 745234 reaction equation
[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH:6]1[NH:11][CH2:10][CH2:9][NH:8][C:7]1=[O:12].Cl[CH2:14][C:15]([O:17][CH3:18])=[O:16]>>[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH:6]1[N:11]([CH2:14][C:15]([O:17][CH3:18])=[O:16])[CH2:10][CH2:9][NH:8][C:7]1=[O:12]

Participants

3

Reactant 2

HCID 7295Methyl chloroacetateHCID 65649Piperazinone, 3-(2-thienyl)- (9CI)

Product 1

HCID 13120682HCID 13120682, compound

Procedure

18.2 g (0.1 mol) of 3-(2-thienyl)-piperazin-2-one, prepared in accordance with Example 16, are reacted with methyl chloroacetate and worked up, as described in Example 6.

Sources & evidence

ORD record
ord-85fe66ebda6d436f8ed7208079635df5
Source dataset
uspto-grants-1986_07
Patent number
US04598079

Reaction notes

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