Benzyl Chloride → HCID 13120696, compound

HRID 745238Notes

Reaction equation

HRID 745238 reaction equation
[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[C:3]([CH:10]2[NH:15][CH2:14][CH2:13][NH:12][C:11]2=[O:16])=[CH:2]1.[CH2:17](Cl)[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1>>[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[C:3]([CH:10]2[N:15]([CH2:17][C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=3)[CH2:14][CH2:13][NH:12][C:11]2=[O:16])=[CH:2]1

Participants

3

Reactant 2

HCID 7503Benzyl ChlorideHCID 131206953-(1H-Indol-3-yl)-2-piperazinone

Product 1

HCID 13120696HCID 13120696, compound

Procedure

21.5 g (0.1 mol) of 3-(3-indolyl)-piperazin-2-one, prepared in accordance with Example 30, are alkylated with benzyl chloride as described in Example 2.

Sources & evidence

ORD record
ord-87c5226f869040dab7f29247c923b95b
Source dataset
uspto-grants-1986_07
Patent number
US04598079

Reaction notes

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