4-Cyanobenzaldehyde → HCID 53694269, compound

Participants

Reaction Steps

Into 800 ml of anhydrous methanol, was dissolved 35.5 g of 4-phthalimidomethylbenzyltriphenylphosphonium bromide. To the resulting solution, through which argon had been passed with stirring for 5 minutes, was added at room temperature slowly dropwise 11.6 ml of anhydrous methanol containing 28% of sodium methoxide. After 10 minutes, 7.9 g of p-cyanobenzaldehyde was added to the reaction mixture and the mixture was stirred at room temperature for 15 hours. The precipitated crystals were collected by filtration to obtain 15.4 g of 4-[2-(4-phthalimidomethylphenyl)ethenyl]benzonitrile.

Provenance & Evidence