Methanol → HCID 178484914, compound

Participants

Reaction Steps

To a solution of 1.5 g of methyl 4-[2-(4-phthalimidomethylphenyl)ethyl]benzimidate hydrochloride in 150 ml of chloroform, was added 0.3 ml of a methanol solution containing 40% of methylamine. The mixture was stirred at room temperature for 15 hours. The reaction mixture was stripped of the solvent under reduced pressure. Ether was added to the residue and the precipitated crystals were collected by filtration to yield 1.3 g of N-methyl-4-[2-(4-phthalimidomethylphenyl)ethyl]benzamidine hydrochloride; m.p. 270° C. or above.

Provenance & Evidence