Isopropyl iodide → HCID 12788092, compound

HRID 745303Notes

Reaction equation

HRID 745303 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][C:12]=1[O:13][CH3:14])[C:9]1=[CH:15][C:16](=[O:20])[NH:17][C:18](=[O:19])[N:8]1[CH2:7][CH2:6]2.[CH:21](I)([CH3:23])[CH3:22]>>[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][C:12]=1[O:13][CH3:14])[C:9]1=[CH:15][C:16](=[O:20])[N:17]([CH:21]([CH3:23])[CH3:22])[C:18](=[O:19])[N:8]1[CH2:7][CH2:6]2

Participants

3

Reactant 2

HCID 6362Isopropyl iodideHCID 908572HCID 908572, compound

Product 1

HCID 12788092HCID 12788092, compoundYield 50%

Procedure

In a manner analogous to that of Example 3, 9,10-dimethoxy-3,4,6,7-tetrahydro-2H-pyrimido(6,1-a)isoquinolin-2,4-dione is reacted with isopropyl iodide. Yield 50%; melting point 190°-192° C.

Sources & evidence

ORD record
ord-c328c558301040f6b1649d4c85ac3bd9
Source dataset
uspto-grants-1986_07
Patent number
US04598148

Reaction notes

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