HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → Ethyl 2-(2-aminothiazol-4-yl)-2-(2-benzoyloxyethoxyimino)acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Sodium Acetate | HCID 517045 | — |
| Reactant | Thiourea | HCID 2723790 | — |
| Reactant | Ethyl 2-(2-benzoyloxyethoxyimino)-4-chloro-3-oxobutyrate | HCID 53906646 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | Ethyl 2-(2-aminothiazol-4-yl)-2-(2-benzoyloxyethoxyimino)acetate | HCID 53954764 | 42.3% |
Reaction Steps
Ethyl 2-(2-benzoyloxyethoxyimino)-4-chloro-3-oxobutyrate (syn isomer, 20 g.), thiourea (7.76 g.), sodium acetate (8.37 g.), water (75 ml.) and ethanol (75 ml.) were treated in a similar manner to that of Example A-(3) to give ethyl 2-(2-aminothiazol-4-yl)-2-(2-benzoyloxyethoxyimino)acetate (syn isomer, 9 g.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04598147 |
| Source dataset | uspto-grants-1986_07 |
| ORD ID | ord-80ad761531f74804b3c2dc823b23ad46 |
| Source note | uspto-grants-1986_07 |