HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → HCID 53696866, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | 1-Methylimidazole | HCID 1390 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 54161423 | HCID 54161423 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 53696866 | HCID 53696866 | 93.7% |
Reaction Steps
Ethyl 2-(2-aminothiazol-4-yl)-2-(4-methylbenzyloxyimino)acetate (syn isomer, 4.00 g.), 1N sodium hydroxide solution (19.5 ml.), 1-methylimidazole (214 mg.), methanol (40 ml.) and tetrahydrofuran (25 ml.) were treated in a similar manner that of Example P-(4) to give 2-(2-aminothiazol-4-yl)-2-(4-methylbenzyloxyimino)acetic acid (syn isomer, 3.42 g.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04598147 |
| Source dataset | uspto-grants-1986_07 |
| ORD ID | ord-e853ab3e684d47a7bb99b7bd4acf3cd0 |
| Source note | uspto-grants-1986_07 |