反应详情

1.05 g. of 1,3-dihydroxy-5-(5-methoxy-2-pentyl)- benzene and 1.06 g. (6 mmoles) of 1-(2-hydroxy-2-propyl)- 4methoxy-1,4-cyclohexadiene [R.A. Archer et. al. J. Org. Chem., 42, 2277 (1977)]are dissolved in 25 ml. of abs. benzene. 0.5 ml. (3.4 mmoles) of borontrifluoride etherate are added and the mixture is stirred at room temperature for 5 hours. Further 0.40 g. (2.4 mmoles) diene are added and the mixture is stirred overnight. The solution is poured off from the precipitated gum and extracted with 3 ×10 ml. of 1 N sodium hydroxide. The benzene solution is dried, evaporated and the residue is chromatographed on a column with a 8.1 mixture of benzene: ethyl acetate. The product is a colorless resin.

1. dissolution, 42, 2277 (1977)]are dissolved in 25 ml
2. stirringthe mixture is stirred overnight
3. additionThe solution is poured off from the precipitated gum
4. extractionextracted with 3 ×10 ml
5. dry with materialThe benzene solution is dried
6. customevaporated
7. customthe residue is chromatographed on a column with a 8.1 mixture of benzene