Methanesulfonyl chloride → HCID 23313763, compound

HRID 745551Notes

Reaction equation

HRID 745551 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][CH2:10][CH:11]2[C:16](=[O:17])[CH:15]3[CH2:18][CH2:19][N:12]2[CH2:13][CH2:14]3)=[CH:4][CH:3]=1.[CH3:20][S:21]([Cl:24])(=[O:23])=[O:22]>>[ClH:24].[O:17]=[C:16]1[CH:15]2[CH2:18][CH2:19][N:12]([CH2:13][CH2:14]2)[CH:11]1[CH2:10][CH2:9][CH2:8][C:5]1[CH:4]=[CH:3][C:2]([NH:1][S:21]([CH3:20])(=[O:23])=[O:22])=[CH:7][CH:6]=1

Participants

3

Reactant 2

HCID 31297Methanesulfonyl chlorideHCID 23313728HCID 23313728, compound

Product 1

HCID 23313763HCID 23313763, compound

Procedure

In a manner similar to Example X, react 2-[3-(4-aminophenyl)propyl]-1-azabicyclo[2.2.2]octan-3-one with methanesulfonyl chloride to afford the title compound.

Sources & evidence

ORD record
ord-8099637394d0443fb235760012a297fe
Source dataset
uspto-grants-1986_07
Patent number
US04599344

Reaction notes

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