Methanesulfonyl chloride → HCID 23313722, compound
Reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][CH2:10][CH:11]2[CH2:16][CH:15]3[CH2:17][CH2:18][N:12]2[CH2:13][CH2:14]3)=[CH:4][CH:3]=1.[CH3:19][S:20]([Cl:23])(=[O:22])=[O:21]>>[ClH:23].[N:12]12[CH2:13][CH2:14][CH:15]([CH2:17][CH2:18]1)[CH2:16][CH:11]2[CH2:10][CH2:9][CH2:8][C:5]1[CH:6]=[CH:7][C:2]([NH:1][S:20]([CH3:19])(=[O:22])=[O:21])=[CH:3][CH:4]=1Participants
3
Procedure
In a manner similar to Example X react 2-[3-(4-aminophenyl)propyl]-1-azabicyclo[2.2.2]octane with methanesulfonyl chloride to give the title compound.
Sources & evidence
- ORD record
- ord-70bbdbc3686242fabbd61d57f59ec8b6
- Source dataset
- uspto-grants-1986_07
- Patent number
- US04599344
Reaction notes
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