反应详情

5.70 g (18.0 mmol) 3-(1-benzyl-1,2,3,6-tetrahydro-pyridin-4-yl)-quinolin-2-ol were placed in 200 mL methanol. 1.00 g palladium on charcoal (10%) were added and the reaction mixture was hydrogenated for 3 h at 50° C. under a hydrogen atmosphere. The catalyst was removed by suction filtering and the mother liquor was concentrated to dryness by rotary evaporation. The residue was triturated with diethyl ether and the undissolved solid was suction filtered and dried.

1. customThe catalyst was removed by suction
2. filtrationfiltering
3. concentrationthe mother liquor was concentrated to dryness by rotary evaporation
4. customThe residue was triturated with diethyl ether
5. filtrationfiltered
6. customdried