HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 6-nitro-2,3-dihydro-1H-inden-5-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | N-(6-nitro-2,3-dihydro-1H-inden-5-yl)acetamide | HCID 10751392 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 6-nitro-2,3-dihydro-1H-inden-5-amine | HCID 2763604 | 92.3% |
Reaction Steps
14.6 g of 5-acetamino-6-nitro-indane were boiled under reflux overnight in 1.5 l of methanol with 300 ml of hydrochloric acid in methanol and then evaporated. 11.8 g of crude product were recrystallized from acetonitrile. There were obtained 10.9 g (92.3% of theory) of 5-amino-6-nitro-indane of melting point 131°-132° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04599347 |
| Source dataset | uspto-grants-1986_07 |
| ORD ID | ord-3362798d1b5f42c78f7bdb698477850f |
| Source note | uspto-grants-1986_07 |