HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → N-[2-(benzo[b]thien-3-yl)ethyl]adenosine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Benzo[b]thiophene-3-ethanamine | HCID 26743 | — |
| Reactant | 6-Chloropurine riboside | HCID 93003 | — |
| Product | N-[2-(benzo[b]thien-3-yl)ethyl]adenosine | HCID 13686648 | — |
Reaction Steps
The title compound was prepared as in Example 1 using 6-chloropurine riboside (1.15 g, 4 mmol), 2-(3-benzo[b]thienyl)ethylamine.HCl (CAS Number 148585-66-1) (1.0 g, 4.6 mmol), and triethylamine (1.1 g, 11 mmol); yield 1.5 g (88%), mp 173°-174° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04600707 |
| Source dataset | uspto-grants-1986_07 |
| ORD ID | ord-790aec2e81724fdea4398bba36dbd51b |
| Source note | uspto-grants-1986_07 |