Methyl iodide → HCID 178503555, compound

HRID 745759Notes

Reaction equation

HRID 745759 reaction equation
[CH3:1][CH:2]1[NH:6][C:5](=[S:7])[NH:4][C:3]1=[O:8].[CH3:9][I:10]>C(O)C>[IH:10].[CH3:9][S:7][C:5]1[NH:6][CH:2]([CH3:1])[C:3](=[O:8])[N:4]=1

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 30329074-Imidazolidinone,5-methyl-2-thioxo-(9CI)

Product 1

HCID 178503555HCID 178503555, compoundYield 57%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A solution of 5-methyl-2-thiohydantoin (15 g.) and methyl iodide (16.3 g.) in dry ethanol (130 ml.) was heated under reflux for 11/2 hours, and then allowed to stand at 0° overnight. The crystalline product was filtered and washed with ether to give 2-methylthio-5-methyl-2-imidazolin-4-one hydroiodide (17.8 g.), m.p. 170°-173°.

Workup

  1. temperatureunder reflux for 11/2 hours
  2. filtrationThe crystalline product was filtered
  3. washwashed with ether

Sources & evidence

ORD record
ord-8772bba05c8f43f79b51234e0f1a4230
Source dataset
uspto-grants-1986_07
Patent number
US04600720

Reaction notes

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