2-Methoxyethanol → 3-(2-Methoxy-ethyl)-1,3-dihydro-indol-2-one

Participants

Reaction Steps

2.0 g (15 mmol) indolin-2-one, 5 mL (63 mmol) 2-methoxyethanol and 1.5 g Raney nickel in 20 mL THF were stirred for 4 h at 200° C. in an autoclave. After the catalyst had been filtered off the mother liquor was evaporated down, the residue was triturated with diisopropylether, suction filtered and dried

Provenance & Evidence