4-Methylcatechol → 4-(4-Chloro-3-nitrophenylsulphonyl)-5-methyl-1,2-benzenediol

Participants

Reaction Steps

66 g (297.8 mmol) of 4-chloro-3-nitrobenzenesulphinic acid (produced by reduction of 4-chloro-3-nitrobenzenesulphonyl chloride with sodium sulphite) are condensed with 41.95 g (337.9 mmol) of 4-methyl-1,2-benzenediol in a manner analogous to that described in Example 4, yielding 4-(4-chloro-3-nitrophenylsulphonyl)-5-methyl-1,2-benzenediol in the form of crystals having a melting point of 196°-197° (from ethyl acetate/hexane).

Provenance & Evidence