Hydrochloric Acid → HCID 23312070, compound

Participants

Reaction Steps

10.9 g (0.0264 mole) of ethyl 5-chloro-6-(3,4-methylenedioxyphenylsulfonyl)-1,3-benzodioxole-2-carboxylate are covered with 40 ml of 2-n sodium hydroxide solution and the batch is heated for half an hour in a boiling water bath, cooled, acidified with hydrochloric acid and then extracted with ethyl acetate, affording 5-chloro-6-(3,4-methylenedioxyphenylsulfonyl)-1,3-benzodioxole-2-carboxylic acid. Melting point 182°-184° C. (crystallisation from ethyl acetate/toluene).

Provenance & Evidence