Sodium Hydroxide → HCID 23312050, compound

HRID 745812Notes

Reaction equation

HRID 745812 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([S:9]([C:12]2[C:25]([CH3:26])=[CH:24][C:15]3[O:16][CH:17]([C:19]([O:21]CC)=[O:20])[O:18][C:14]=3[CH:13]=2)(=[O:11])=[O:10])[CH:5]=[C:6]([Cl:8])[CH:7]=1.[OH-].[Na+]>>[Cl:8][C:6]1[CH:5]=[C:4]([S:9]([C:12]2[C:25]([CH3:26])=[CH:24][C:15]3[O:16][CH:17]([C:19]([OH:21])=[O:20])[O:18][C:14]=3[CH:13]=2)(=[O:10])=[O:11])[CH:3]=[C:2]([Cl:1])[CH:7]=1

Participants

3

Reactant 2

HCID 14798Sodium HydroxideHCID 23312137HCID 23312137, compound

Product 1

HCID 23312050HCID 23312050, compound

Procedure

8.38 g (0.02 mole) of ethyl 5-(3,5-dichlorophenylsulfonyl)-6-methyl-1,3-benzodioxole-2-carboxylate are covered with 30 ml of 2-n sodium hydroxide solution and the batch is heated for 1 hour in a boiling water bath, cooled and acidified, affording 5-(3,5-dichlorophenylsulfonyl)-6-methyl-1,3-benzodioxole-2-carboxylic acid. Melting point 210°-214° C. (crystallisation from ethyl acetate/toluene).

Workup

  1. temperaturethe batch is heated for 1 hour in a boiling water bath
  2. temperaturecooled

Sources & evidence

ORD record
ord-a7bc81b4c4cb4ad6b490f9dcad439f3b
Source dataset
uspto-grants-1986_07
Patent number
US04600709

Reaction notes

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