Nitric Acid → HCID 70467132, compound

Participants

Reaction Conditions

Reaction Steps

86.8 g of N-acetyl-2,2,4-trimethyltetrahydroquinoline are dissolved in 600 ml of acetic anhydride and the solution is cooled to 0° C. 28 g of fuming nitric acid in 50 ml of acetic anhydride are now added dropwise. The mixture is kept at 0° C. for a further 30 minutes and is then stirred overnight at room temperature. It is poured onto water and the precipitate is filtered off with suction. 89 g of 1-acetyl-2,2,4-trimethyl-6-nitrotetrahydroquinoline of melting point 91° C. are obtained.

Provenance & Evidence