HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phthalic Anhydride → Fluorescein phthalamic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phthalic Anhydride | HCID 6811 | — |
| Reactant | 5-Aminofluorescein | HCID 76845 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | Fluorescein phthalamic acid | HCID 131714783 | — |
Reaction Steps
A mixture of 350 mg (0.001 mol) of 5-aminofluorescein and 200 mg of phthalic anhydride in 5 milliliters of glacial acetic acid was stirred at ambient temperature for 48 hours. The yellow reddish product was filtered and washed once with acetic acid and twice with diethyl ether. 460 Mg of fluorescein-phthalamic acid was obtained. I.R (KBR) showed bands at 3060; 3000; 1685; 1590; 1540; 1480; 1460; 1430; 1350; 1310; 1270; 1230; 1195; 1150; and 1115 cm-1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04600775 |
| Source dataset | uspto-grants-1986_07 |
| ORD ID | ord-7cbb0db406bd487cad6863495797162b |
| Source note | uspto-grants-1986_07 |