Bromine → HCID 23310926, compound

HRID 745892Notes

Reaction equation

HRID 745892 reaction equation
[CH2:1]([C:4]1[CH:9]=[CH:8][C:7]([C:10]2[NH:15][NH:14][C:13]([S:16][CH3:17])=[N:12][N:11]=2)=[CH:6][CH:5]=1)[CH2:2][CH3:3].BrBr>C(O)(=O)C>[CH2:1]([C:4]1[CH:5]=[CH:6][C:7]([C:10]2[N:11]=[N:12][C:13]([S:16][CH3:17])=[N:14][N:15]=2)=[CH:8][CH:9]=1)[CH2:2][CH3:3]

Participants

4

Reactant 2

HCID 24408BromineHCID 178438908HCID 178438908, compound

Product 1

HCID 23310926HCID 23310926, compoundYield 84.7%

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

0.0163 Mol (4.05 g) of 6-(4-n-propylphenyl)-3-methylthio-1.2-dihydro-1,2,4,5-tetrazine is dissolved in 80 ml crystalline acetic acid at 40° C. and 18 ml of a 1-molar Br2 -crystalline acetic acid solution is added dropwise. The solution is stirred for one hour and subsequently poured over ice water. The red dyestuff is vacuum dried, washed with water and dried. Recrystallization from ethanol provides 3.4 g of red crystals. M.pt.: 78°-79° C. The compounds characterized in Table 7 are made in an analogous fashion manner.

Workup

  1. customdried
  2. washwashed with water
  3. customdried
  4. customRecrystallization from ethanol

Sources & evidence

ORD record
ord-770f8cc671fa49faa4be3c5613375e03
Source dataset
uspto-grants-1986_07
Patent number
US04601846

Reaction notes

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