HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzoic Acid → 1-[2-(4-Benzoylcarbamoylphenoxy)ethyl]imidazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzoic Acid | HCID 243 | — |
| Reactant | 4-(2-(1H-imidazol-1-yl)ethoxy)benzamide | HCID 13569177 | — |
| Reactant | Ethylacetate methanol | HCID 21584119 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 1-[2-(4-Benzoylcarbamoylphenoxy)ethyl]imidazole | HCID 13569201 | — |
Reaction Steps
Treatment of benzoic acid with N,N'-carbonyldiimidazole and 1-[2-(4-carbamoylphenoxy)ethyl]imidazole in dry N,N-dimethylformamide as described in Example 34 gave 1-[2-(4-benzoylcarbamoylphenoxy)ethyl]imidazole, m.p. 152°-154° C. (from methanol/ethyl acetate). Found: C, 67.66; H, 5.16; N, 12.59. C19H17N3O3 requires: C, 68.05; H, 5.11; N, 12.53%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04602016 |
| Source dataset | uspto-grants-1986_07 |
| ORD ID | ord-3d0886a7c62b4a1d813c109f0effdb61 |
| Source note | uspto-grants-1986_07 |